Updated on April 17, 2006

Grey's Anatomy airs at 10 p.m. EST on Sundays on ABC. This season has 26 episodes. Note episode numbering started at 2.01 for the first new episode that aired in September 2005, meaning that the first Season 1 left-over episode was labbeled 2.01.
Special: Grey's Anatomy: Under Pressure
Airdate: April 23, 2006
04/10 - Check into Seattle Grace Hospital and follow Meredith Grey and her fellow interns from their first day on the job through their most recent struggles with surgical training - and each other. Guest starring are Christina Ricci as Hannah the paramedic, Chris O'Donnell as Finn Dandridge, Kate Burton as Ellis Grey, Jeffrey Dean Morgan as Denny Duquette, Loretta Devine as Adele Webber, Kyle Chandler as Dylan Young, Sara Ramirez as Dr. Calliope Torres, Mare Winningham as Eileen Grey and Cress Williams as Tucker Jones. Source: ABC
Episode 2.23: Blues for Sister Someone (fka "Rhythm of Life")
Airdate: April 30, 2006
04/17 - Guest cast: Chris O'Donnell as Finn Dandridge, Sara Ramirez as Callie, Jeffrey Dean Morgan as Denny, Albert Hall as Eugene Foote, Jayne Brook as Gwen Graber and Jean Louisa Kelly as Rose Ward. Source: ABC
04/04 - Izzie grills George about the personal details of his life, Addison takes Alex to task about a sensitive case, and Burke feels the pressure when he treats his musical hero. Source: ABC
03/11 - A Catholic mother of seven, whose highly religious husband refuses to use any kind of contraceptives, begs Addison for medical help. They tell the husband it was a surgical complication. But he's suspicious and she faces legal scrutiny. A divorce attorney sees a prospective client in her team of tending doctors. A legendary jazz musician refuses to see medical reason. Source: SpoilerFix.com
03/08 - Derek — after an impromptu exam-room consult with Seattle's best divorce attorney — will come closer than ever to subtracting Addison from his life. Source: Ask Ausiello @ TV Guide
03/01 - While waiting at the vet's office, Meredith meets Sam, a confident man who later cooks her breakfast. Sensing her wariness, he doesn't hesitate on treating her with blunt honesty. Source: SpoilerFix.com [Note: Sam is Chris O'Donnell's character that was renamed Finn. This spoiler was supposed to happen in 2.22 but it seems the scene was moved in 2.23 per the previews.]
Episode 2.24: Damage Case
Airdate: May 7, 2006
04/07 - The interns deal with a family involved in a car accident, Derek lets his emotions get the best of him, and Burke and Izzie make a new suggestion to Denny. Source: ABC
04/03 - That bisexual storyline? NOT gonna happen. At least not this season. That’s what I’m told. The storyline was apparently changed. Source: Kristin on E!Online
03/21 - The staff attends to Marshall, an intern at another hospital who starts a chain reaction car accident and struggles with short-term memory loss when he wakes. Also requiring care are married, expecting couple Melanie and Noah and her parents, who crashed into her side of the car when they were hit. The family is relieved when tests show the baby to be fine. Noah patiently acts as buffer for his loud, Southern wife and in-laws. Later in the episode, female doctors meet with an old friend who may be closer than expected. Source: SpoilerFix.com
03/17 - My casting spies are telling me producers are looking for an actress to play a woman in her forties who shows up at Seattle Grace with a bisexual bombshell up her sleeve about one of the female interns. Source: The Ausiello Report
03/13 - My sources tell me that later on this season, we are going to find out that one of the main characters is hiding a secret… One that they have kept in the closet… [The person is] bisexual, actually, from what I hear. My sources tell me that in an upcoming episode, we are going to meet this character’s same-sex love interest. Source: Kristin on E!Online
Episode 2.25: 17 Seconds (Part 1 of season finale)
Airdate: May 14, 2006
04/01 - The team meets new (recurring) Erica, whose personality is similar to Bailey, but the doctors would never argue with the Nazi like they do her. Parents faced with losing their daughter demand the hospital keep her alive long enough for her baby's birth. The staff tolerates an egotistical patient. After leaving the hospital, a newly empowered busboy stays at his job out of loyalty to the only owner who treats him decently. One doctor's overreaction unites two bickering patients. Source: SpoilerFix.com
Episode 2.26: Deterioration of the Fight or Flight Response (Part 2 of season finale)
Airdate: Monday May 15, 2006 from 9 to 11 p.m.
04/12 - I'm hearing [that Meredith has to choose between Derek and Chris O'Donnell's character in the Grey's Anatomy finale.] Source: Ask Ausiello @ TV Guide
04/10 - Grey’s is looking to cast a couple recurring characters. I’m told one will be an African American high school kid called Heath and the other one is also an African American high school student named Nicole Webber… who I’m hoping has some relation to a certain Dr. Richard Webber… Source: Kristin on E!Online [Note: It is possible we see both teens earlier in the season.]
04/06 - This episode will feature two high school seniors with recurring roles. One, Nicole, faces an overprotective mother and quietly supportive father while considering a surgery with a 20% failure rate. Another begs his parents to keep to their original decision regardless of the risk. Source: SpoilerFix.com

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